Clinical Trial: Adaptive Family Treatment for Adolescent Anorexia Nervosa

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Adaptive Family Treatment for Adolescent Anorexia Nervosa

Brief Summary: Anorexia Nervosa (AN) has the highest mortality rate compared to any other psychiatric disorder. The most promising treatment for adolescents with AN is family-based treatment (FBT). However, only 50% of patients receiving FBT fully remit at 12-month follow-up. Consequently, providing an alternative therapy early in the treatment course for those not responding to FBT may enhance overall outcome. This study aims to develop a new treatment - Intensive Family-Focused Treatment (IFT) - to improve outcomes in those adolescents, aged 12-18 years, who do not show an early response to FBT.

Detailed Summary:
Sponsor: Stanford University

Current Primary Outcome: Full remission from AN (%MBW>95) [ Time Frame: End of Treatment (6 months) ]

Weight restoration to at least 95% of Median body weight (calculated by height, weight, gender, and age)


Original Primary Outcome: Same as current

Current Secondary Outcome: Changes in subscale scores of the EDE [ Time Frame: End of Treatment (6 months) ]

Eating Disorder Examination subscale measures (weight concern, shape concern, dietary restraint) within 1 standard deviation of normative scores.


Original Secondary Outcome: Same as current

Information By: Stanford University

Dates:
Date Received: April 5, 2012
Date Started: September 2011
Date Completion:
Last Updated: April 12, 2016
Last Verified: April 2016