Clinical Trial: Magnesium Sulfate vs Placebo for Placental Abruption

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional

Official Title: Randomized, Double Blind Trial of Magnesium Sulfate Tocolysis Versus Intravenous Saline for Suspected Placental Abruption

Brief Summary: To evaluate the safety and efficacy of magnesium sulfate for preterm suspected abruption.

Detailed Summary: We hope to learn if there is a difference in the efficacy of intravenous magnesium sulfate versus intravenous saline infusion in the resolution of vaginal bleeding and contractions in patients with a suspected placental abruption.
Sponsor: Stanford University

Current Primary Outcome: Undelivered With Resolution of Vaginal Bleeding and Contractions in First 48 Hours [ Time Frame: 48 hours after the randomization ]

The primary outcome was the proportion of women undelivered at 48 hours with resolution of vaginal bleeding and uterine contractions.


Original Primary Outcome: resolution of vaginal bleeding and contractions

Current Secondary Outcome:

  • Gestational Age at Delivery (Weeks) [ Time Frame: Time of delivery ]
    Median gestational age at delivery (in full weeks)
  • Neonatal Apgar Score at 5 Minutes [ Time Frame: At 5 minutes after birth ]
    The median Apgar score at 5 minutes. Apgar score scale is from 0 to 10 with score 0 expressing the worst neonatal status and score 10 the best status.


Original Secondary Outcome:

  • preterm delivery
  • neonatal outcomes


Information By: Stanford University

Dates:
Date Received: September 13, 2005
Date Started: March 2004
Date Completion: June 2017
Last Updated: March 9, 2017
Last Verified: March 2017