Clinical Trial: Laparoscopic Cholecystectomy for Acute Cholecystitis After 72 Hours of Symptoms
Study Status: Terminated
Recruit Status: Terminated
Study Type: Interventional
Official Title: Laparoscopic Cholecystectomy for Acute Cholecystitis: is the Rule of 72 Hours Still Actual?
Brief Summary: The purpose of this study is to compare the clinical outcomes of early versus delayed laparoscopic cholecystectomies for acute cholecystitis with more than 72 hours of symptoms.
Detailed Summary: In acute biliary cholecystitis, there was a dogma that patients should be operated within 72 hours of evolution. However, retrospective studies suggested that laparoscopic cholecystectomy even after 72 hours was safe. Moreover, some randomized controlled-trials did not found any differences in term of complications between early and delayed cholecystectomy, however none of these studies did separate patients according to the onset of symptoms. The aim of our present study was to compare the clinical outcomes of immediate versus delayed cholecystectomies for acute cholecystitis with more than 72 hours of symptoms.
Sponsor: University of Lausanne Hospitals
Current Primary Outcome: Global morbidity [ Time Frame: 30 postoperative days ]
Original Primary Outcome:
- Global morbidity
- Postoperative complications
Current Secondary Outcome:
- Postoperative complications [ Time Frame: 30 postoperative days ]
- Length of stay [ Time Frame: 30 postoperative days ]
Original Secondary Outcome: Cost analysis
Information By: University of Lausanne Hospitals
Dates:
Date Received: March 5, 2012
Date Started: February 2009
Date Completion:
Last Updated: December 29, 2015
Last Verified: December 2015
