Clinical Trial: Intensive Arterial Pressure Control in Acute Coronary Syndrome

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Interest of an Intensive Arterial Pressure Control in Acute Coronary Syndrome

Brief Summary:

The intensive arterial pressure control in acute coronary syndrome (ACS) during the first 24 hours can improve the prognosis in the short and long term.

We confront two treatment strategies (standard and intensive treatment) to evaluate their superiority in the treatment of acute coronary syndrome.


Detailed Summary:

Acute coronary syndrome is often associated with arterial pressure elevation which are deleterious for the heart and needs urgent intervention to lower the blood pressure to the required values, however there is no clear recommendations concerning the treatment intensity in this situation.

The investigators know that high arterial pressure increases the oxygen myocardial consumption and it is deleterious in acute coronary syndrome, so , it is logical to reduce intensively this pressure.


Sponsor: University of Monastir

Current Primary Outcome:

  • mortality [ Time Frame: 1 month ]
    mortality at one month.
  • mortality [ Time Frame: 6 months ]
    mortality at six months.
  • mortality [ Time Frame: 1 year ]
    mortality at one year.


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • recurrence of chest pain [ Time Frame: during hospital admission ]
    chest pain recurrence was noted during patients hospital stay in emergency or cardiology departments
  • Acute Coronary Syndrome complication [ Time Frame: during hospital admission ]
    ACS complications such as cardiogenic shock, arrythmias, conduction troubles... were noted during patients hospital stay in emergency or cardiology departments
  • revascularisation [ Time Frame: at hospital admission and during the followup period of one year ]
    acts of revascularisation were noted for all patients during their hospital stay and over a one year followup period
  • stroke [ Time Frame: 1 month, 6 months and 1 year period ]
    stroke events were noted for patients during the followup period of one month, six months and one year.
  • non cardiac deaths [ Time Frame: over the 1 year followup period ]
    non cardiac deaths were investigated during the one year followup period.


Original Secondary Outcome: Same as current

Information By: University of Monastir

Dates:
Date Received: March 27, 2014
Date Started: October 2013
Date Completion: September 2015
Last Updated: May 16, 2014
Last Verified: May 2014