Clinical Trial: Confusion in the Elderly After Colon Surgery

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Observational

Official Title: Cognitive Changes After Surgery in the Elderly: Does Minimally Invasive Surgery Influence the Incidence of Postoperative Cognitive Changes Compared to Open Colon Surgery?

Brief Summary: A study will be conducted to determine if there is any cognitive benefit in elderly patients having open versus minimally invasive colon cancer surgery.

Detailed Summary: Cognitive changes in the elderly are common after surgery. It is not known if minimally invasive or laparoscopic surgery can prevent these changes. A study will be conducted on patients scheduled to have abdominal surgery. The patients will have cognitive evaluations before and after surgery. A small amount of blood, about 2 tablespoons, will be collected no more than 5 times in 6 months. The results will be analyzed to determine if there are changes between those having open surgery versus patients having laparoscopic or minimally invasive surgery, and if these changes coincide with cognitive changes.
Sponsor: New York Hospital Queens

Current Primary Outcome: Confusion [ Time Frame: 6 Months ]

Confusion assessed by questionaires and cognitive testing


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • degree of inflammation [ Time Frame: 6 Months ]
    5 separate blood draws
  • presence of electrolyte imbalance [ Time Frame: 6 months ]
    5 separate blood draws
  • pituitary-thyroid axis disruption [ Time Frame: 6 months ]
    5 separate blood draws
  • liver function tests [ Time Frame: 6 months ]
    5 separate blood draws
  • nutritional status [ Time Frame: 6 months ]
    5 separate blood draws


Original Secondary Outcome: Same as current

Information By: New York Hospital Queens

Dates:
Date Received: April 23, 2012
Date Started: January 2012
Date Completion: January 2015
Last Updated: June 15, 2012
Last Verified: June 2012