Clinical Trial: A Study With INCB018424 Phosphate Cream Applied Topically to Subjects With Alopecia Areata (AA)

Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional

Official Title: An Open-Label (Part A) and a Double-Blind, Randomized, Placebo Controlled (Part B) Study, With an Open-Label Extension, of INCB018424 Phosphate Cream Applied Topically to Subjects With Alopecia Areata

Brief Summary: A phase 2 study to find out if the drug INCB018424 Phosphate Cream is safe and has beneficial effects in people who have alopecia areata (partial or complete hair loss) when applied to the skin.

Detailed Summary:
Sponsor: Incyte Corporation

Current Primary Outcome: Percentage of subjects achieving a Severity of Alopecia Tool score (SALT) 50 response in terminal hair (pigmented and nonpigmented) at Week 24 [ Time Frame: 24 weeks ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Mean change from Baseline in SALT score through Week 24 [ Time Frame: 24 weeks ]

Original Secondary Outcome: Same as current

Information By: Incyte Corporation

Dates:
Date Received: September 16, 2015
Date Started: October 2015
Date Completion: January 2019
Last Updated: April 17, 2017
Last Verified: April 2017