Clinical Trial: Study of the Influence of the Moon and Seasons On Outcomes Following Surgery To Repair Ascending Aortic Dissection
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: The Influence of Lunar Cycle On Hospital Outcomes Following Ascending Aortic Dissection Repair
Brief Summary: That the full-moon stage of the lunar cycle is associated with reduced mortality and shorter length of stay in patients undergoing repair of aortic dissection, after adjusting for seasonal effects, demographics and cardiovascular risk factors.
Detailed Summary:
The primary objective of this study is to determine whether the findings of Shuhaiber et al. [2013] (see citations) may be confirmed using national audit data from the United Kingdom.
A cohort of all acute ascending aortic dissection repair surgeries will be extracted from the National Adult Cardiac Surgery Audit (NACSA) database. The current dataset version 4.12, available for download from the website of the National Institute for Cardiovascular Outcomes Research (see links), contains 168 fields that detail pre-operative patient characteristics, operative details and post-operative outcomes. The dataset is revised intermittently to meet the requirements of users and to respond to changes in the management of adult cardiac surgery; however, the fields to be analysed in this study have not been subject to any documented revisions. The extracted data are to be cleaned using version 9.9 of the NACSA cleaning algorithm.
Seasons are to be coded in the same way as in the published study: autumn (September 21 through December 20), winter (December 21 through March 21), spring (March 22 through June 21) and summer (June 22 through September 20).
Three definitions are to be used for the phases of the moon. The first definition mirrors that employed in the motivating work: each lunar cycle from new moon to new moon is to be split into four parts and labelled "New", "Waxing", "Full" and "Waning". The second definition centers each of those four labels around the named event: i.e., the "New" period is to be centered around the new moon event itself, instead of starting on the day of a new moon as in the first definition. The third definition will split the lunar cycle into 8 event-centred periods, called "New", "Waxing c
Sponsor: 22EON
Current Primary Outcome:
- All cause in-hospital mortality [ Time Frame: During hospital stay, an expected average of 8 days ]
- Length of stay in hospital among survivors to discharge [ Time Frame: During hospital stay, an expected average of 18 days ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: 22EON
Dates:
Date Received: September 8, 2014
Date Started: January 1998
Date Completion:
Last Updated: September 9, 2014
Last Verified: September 2014
