Clinical Trial: Amlodipine on Blood Flow of Preovulatory Follicle in Polycystic Ovarian Patients

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Effect of Amlodipine and Clomid on Blood Flow of Preovulatory Follicle in Polycystic Ovarian Patients

Brief Summary: On the basis of the current study, amlodipine seems to be a promising drug on improving uterine, ovarian blood flow, size of pre-ovulatory follicle, midluteal progesterone level and pregnancy outcome in patients with pco.

Detailed Summary: To know if amlodipine has vasodilator effect on ovarian ar. In pco patient.
Sponsor: Ahmed Fathy Ali Mohamed Ghanem

Current Primary Outcome: change in ovarian artery perfusion [ Time Frame: day number five and day number 9 of menstrual cycle ]

peak systolic velocity ( psv ) measured by doppler u/s


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Number of mature follicle [ Time Frame: day 14 of menstrual cycle ]
    by vaginal u/s
  • endometrial thickening [ Time Frame: day number five and day number 9 of menstrual cycle ]
    by vaginal u/s


Original Secondary Outcome: Same as current

Information By: Ain Shams Maternity Hospital

Dates:
Date Received: August 27, 2015
Date Started: January 2015
Date Completion:
Last Updated: March 24, 2016
Last Verified: March 2016