Clinical Trial: Characterization of Local and Systemic Bone Markers in Diabetes Patients With Charcot Osteoarthropathy

Study Status: Enrolling by invitation
Recruit Status: Enrolling by invitation
Study Type: Observational

Official Title:

Brief Summary:

The study is designed to investigate biomarkers related to bone turnover in diabetics with charcot foot. This is done by measuring local blood samples in the feet, and systemically in a vene and an artery. Measurements are done before and after cooling the feet in icewater to lower the bloodflow.

Patients will be compared with healthy diabetic controls.


Detailed Summary:
Sponsor: Bispebjerg Hospital

Current Primary Outcome: RANKL [ Time Frame: 10 min between measurements ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

  • osteocalcin [ Time Frame: 10 min between measurements ]
  • CTX-I [ Time Frame: 10 min between measurements ]
  • sRAGE [ Time Frame: 10 min between measurements ]
  • P1NP [ Time Frame: 10 min between measurements ]


Original Secondary Outcome: Same as current

Information By: Bispebjerg Hospital

Dates:
Date Received: February 27, 2015
Date Started: February 2015
Date Completion:
Last Updated: March 6, 2015
Last Verified: March 2015