Clinical Trial: Comparative Autoantibody and Immunologic Cell Marker Study

Study Status: Enrolling by invitation
Recruit Status: Enrolling by invitation
Study Type: Observational [Patient Registry]

Official Title: Comparative Autoantibody and Immunologic Cell Marker Study

Brief Summary: The purpose of this study is to compare immune phenotype, function, and specificity of B lymphocytes from different developmental stages in autoimmune patients to B cells from infectious disease patients and healthy controls.

Detailed Summary: It is essential to analyze the distribution of autoreactive B cells within bone marrow in order to study immature B cell developmental subsets, which are not present in the peripheral blood. Lymphocyte subsets from bone marrow will be characterized as described above for peripheral blood.
Sponsor: Emory University

Current Primary Outcome: Distribution of autoreactive B cells within bone marrow [ Time Frame: Baseline ]

B cells will be analyzed using flow cytometry.


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Emory University

Dates:
Date Received: April 17, 2015
Date Started: August 2012
Date Completion: June 2020
Last Updated: July 15, 2016
Last Verified: July 2016