Clinical Trial: Spanish Bacteriemia Cohort 2016: Epidemiology, Clinical Management and Prognosis Factors

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Spanish Cohort of Bacteriemias 2016: Epidemiology, Clinical Management and Prognostic Factors at Diagnosis.

Brief Summary:

Bacteremia

The Hypothesis of the study are the followings:

  • To demonstrate relevant epidemiologic and clinical changes with potentially impact in the management and prognosis of the patients with bacteremia.
  • Since the diagnosis and management is heterogeneous between centers, we could identify a scenario to improve.
  • To identify quality indicators in the management of bacteremia.
  • To demonstrate that some interventions made by Bacteremia Team pose relevant impact in the prognosis of bacteremia.

Detailed Summary:
Sponsor: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Current Primary Outcome: Epidemiology and prognostic factors of bacteremia episodes. [ Time Frame: From day 0 to day 30 ]

  • Global incidence and per type of acquisition.
  • Global etiology and per type of acquisition.
  • Frequency of multiresistant and emerging microorganism.
  • Source of bacteremia.
  • Clinical severity of presentation.
  • Clinical failure, mortality at day 7, mortality at day 30, recurrence, length of stay and re-admission at hospital.


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Clinical management of patients with bacteremia during the episode. [ Time Frame: From day 0 to day 30 ]
    • Antibiotic therapy used during the episodes (empirical and targeted).
    • Non antibiotic therapy/support therapy used during the episode.
    • Frequency of focus search and adequate control.
  • Differences in the management between types of services, wards and hospitals. [ Time Frame: From day 0 to day 30 ]
    Comparison between different services and hospital wards of variables regarding on the management of episodes.
  • Influence of clinical management in the prognosis. [ Time Frame: From day 0 to day 30 ]
    - Identifying prognostic factors related with mortality, clinical failure and recurrence.
  • Developing and validating a predictive model for early and late mortality. [ Time Frame: From day 0 to day 30 ]
    - Developing and validating a predictive model for mortality based in prognostic factors related with mortality.
  • Quality indicators in the management of bacteremia. [ Time Frame: From day 0 to day 30 ]
    - Identifying quality indicators in the management of episodes of bacteremia.
  • Interventions made by Bacteremia Team. [ Time Frame: From day 0 to day 30 ]
    • Frequency and type of interventions made by Bacteremia Teams.
    • Impact of these interventions in the management and prognosis of episodes.


Original Secondary Outcome: Same as current

Information By: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Dates:
Date Received: April 5, 2017
Date Started: October 2016
Date Completion: January 2018
Last Updated: May 8, 2017
Last Verified: May 2017