Clinical Trial: Amikacin Penetration Into the Cerebrospinal Fluid
Study Status: Withdrawn
Recruit Status: Withdrawn
Study Type: Interventional
Official Title: Amikacin Penetration Into the Cerebrospinal Fluid: Pharmacokinetic/Pharmacodynamic Analysis in Adults With Hospital Acquired Gram-negative Meningitis Associated With Intracranial Pressure Monitoring a
Brief Summary: The limited available data precludes establishing an antibiotic regimen in patients suffering from bacterial meningitis after head trauma, or spontaneous bleeding Understanding the disposition of Amikacin administered intrathecally will enable to propose rational treatment of these patients.
Detailed Summary: The limited available data precludes establishing an antibiotic regimen in patients suffering from bacterial meningitis after head trauma, or spontaneous bleeding Understanding the disposition of Amikacin administered intrathecally will enable to propose rational treatment of these patients.
Sponsor: Rambam Health Care Campus
Current Primary Outcome:
- Bactericidal effect on the causative bacteria
- Blood and CSF AUC/MIC relationship
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Rambam Health Care Campus
Dates:
Date Received: August 8, 2006
Date Started: September 2006
Date Completion:
Last Updated: November 1, 2015
Last Verified: November 2015
