Clinical Trial: Effect of a Fatty Meal on Endoscopic Retrograde Cholangiopancreatography (ERCP)

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Effect of a Fatty Meal on Cannulation at Endoscopic Retrograde Cholangiopancreatography

Brief Summary: This study is to determine if a fatty meal would improve the ERCP procedure.

Detailed Summary:

A fatty meal is a potent stimulator of cholecystikinin (CCK) in human body. The biological effect of CCK is increasing bile secretion and relaxing the sphincter of Oddi. Theoretically, a fatty meal should facilitate the effect on cannulation at ERCP. If a fatty meal can make the major papilla cannulation easier, it may significantly shorten the procedure time for ERCP and even decrease complications of the procedure, since the complication rate of post-ERCP is positively related to the time of the procedure.

Comparison: Approximately one hour before ERCP procedure, patient will have a fatty meal in the study group and normal saline in control group.

Sponsor: Emory University

Current Primary Outcome: a fatty meal in the study group and normal saline in control group [ Time Frame: the procedure time for ERCP ]

Original Primary Outcome: the facilitative effect of a fatty meal on major papilla by measuring the cannulation time; the amount of x-ray exposure during the procedure

Current Secondary Outcome: follow up within 3 days for complication with relation to the cannulation time [ Time Frame: within 3 days ]

Original Secondary Outcome: follow up within 3 days for complication with relation to the cannulation time

Information By: Emory University

Dates:
Date Received: July 25, 2005
Date Started: May 2003
Date Completion:
Last Updated: July 29, 2013
Last Verified: July 2013