Clinical Trial: Preoperative Dual Antiplatelet Therapy: Platelet Function and Influence of Cardiopulmonary Bypass
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Influence of Cardiopulmonary Bypass on Platelet Function in Patients With Preoperative Dual Antiplatelet Therapy:
Brief Summary:
Patients admitted for coronary artery bypass surgery taking antiplatelet medicine have an increased risk for bleeding.
Present study aims to compare the platelet function in two patient groups using different types of heart-lung machine methods.
It is assumed that one of the methods is superior verified by sensitive methods of testing platelet function.
Detailed Summary:
Taking antiplatelet medication before cardiac surgery increases the risk for bleeding.
The surgical procedure and the use of a heart-lung machine may disturb the function of platelets, why measures to protect the existing function of platelets are of prime concern.
The present study aims to compare how two types of heart-lung machine methods influence platelet function in two groups of patients.
The platelet function will be tested before, during and after surgery by the use of two independent methods.
Sponsor: Umeå University
Current Primary Outcome: Assessment of platelet function following cardiopulmonary bypass using platelet aggregometry [ Time Frame: Test of platelet function will be analysed on arrival to the operating room, post cardiopulmonary bypass and on day 1 in the intensive care unit based on the area under the curve depited from the two employed aggremometers ]
Original Primary Outcome: Same as current
Current Secondary Outcome: Postoperative bleeding [ Time Frame: Postoperative bleeding 24 hrs ]
Original Secondary Outcome: Same as current
Information By: Umeå University
Dates:
Date Received: November 21, 2016
Date Started: November 2016
Date Completion: February 2018
Last Updated: December 8, 2016
Last Verified: November 2016
