Clinical Trial: Interpretation Bias Modification for Body Dysmorphic Disorder

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Evaluation of an Internet-Based Treatment for Body Dysmorphic Disorder

Brief Summary: The purpose of this study is to determine whether a computerized intervention designed to reduce appearance and evaluation related interpretation biases will reduce symptoms associated with body dysmorphic disorder.

Detailed Summary: The present study aims to examine the feasibility of a remote treatment for body dysmorphic disorder delivered via the Internet. To evaluate the efficacy of the IBM protocol we have developed in reducing negative appearance and evaluative related interpretations, we will conduct a two-arm randomized controlled trial over the internet. Individuals with a diagnosis of body dysmorphic disorder (N = 40) will be randomized to one of two conditions: 1) IBM or 2) progressive muscle relaxation. Each condition will consist of eight 10-25 minute treatment sessions. Participants will complete two sessions per week for four weeks and will be administered assessments at pre-treatment, one week post-treatment and at 3-month follow-up. We hypothesize that: 1) IBM will lead to greater reductions in BDD symptoms than the PMR condition; 2) IBM will lead to greater reductions in depression, anxiety and suicidal ideation than the PMR condition; 3) IBM will lead to greater reductions in threat interpretations and greater increases in benign interpretations than the PMR condition; 4) The effects of condition on BDD symptoms will be mediated by changes in BDD-related interpretation bias; and 5) The effects of training in the IBM condition will be maintained at the 3-month follow-up assessments.
Sponsor: Florida State University

Current Primary Outcome: Yale-Brown Obsessive Compulsive Scale Modified for Body Dysmorphic Disorder (BDD-YBOCS; Phillips et al., 1997) [ Time Frame: change from baseline at one-week post treatment and 3-months post-treatment ]

Measures past-week BDD symptom severity


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Beck Depression Inventory (BDI-II; Beck, Steer, & Brown, 1996) [ Time Frame: change from baseline at one-week post treatment and 3-months post-treatment ]
    Measures depressive symptom severity
  • Beck Anxiety Inventory (BAI; Steer & Beck, 1997) [ Time Frame: change from baseline at one-week post treatment and 3-months post-treatment ]
    Measure anxious symptom severity
  • Depressive Symptom Index-Suicidality Subscale [ Time Frame: change from baseline at one-week post treatment and 3-months post-treatment ]
    Measure severity of recent suicidality
  • Body Dysmorphic Disorder Word Sentence Association Paradigm (BDD-WSAP; modified from Hindash & Amir, 2011) [ Time Frame: change from baseline at one-week post treatment and 3-months post-treatment ]
    Measure of strength of BDD-related (i.e. evaluation- and appearance- related threat interpretation biases)


Original Secondary Outcome: Same as current

Information By: Florida State University

Dates:
Date Received: December 16, 2015
Date Started: September 2015
Date Completion: August 2017
Last Updated: March 30, 2017
Last Verified: February 2017