Clinical Trial: Quantitative Ultrasound for the Evaluation of Simple Bone Cyst Healing

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Quantitative Ultrasound for the Evaluation of Simple Bone Cyst Healing

Brief Summary: Simple bone cysts (SBCs), also known as unicameral bone cysts (UBCs), are benign bone lesions. Literature to date describes little agreement between clinicians on specific prognostic criteria for the prediction of cyst healing, recurrence or fracture. Evidence has shown that bone mineral density (BMD) is a reliable indicator of risk to SBC patients given its association with the mechanical properties of bone. There has been further exploration into the use of quantitative ultrasound to assess bone density by measuring the velocity of the ultrasound transmission over the bone. To determine whether the QUS can provide prognostic information with respect to cyst healing, recurrence or fracture with a SBC, further study is needed.

Detailed Summary:
Sponsor: The Hospital for Sick Children

Current Primary Outcome: Z-scores obtained using quantitative ultrasound [ Time Frame: 2 years ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Bone specific alkaline phosphatase [ Time Frame: 2 years ]

Original Secondary Outcome: Same as current

Information By: The Hospital for Sick Children

Dates:
Date Received: November 25, 2015
Date Started: October 2016
Date Completion: September 2018
Last Updated: October 12, 2016
Last Verified: October 2016