Clinical Trial: Distal Tibia Sarcoma Treatment Using Allograft Arthrodesis of the Ankle

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Distal Tibia Sarcoma Treatment Using Allograft Arthrodesis of the Ankle

Brief Summary: The study show the clinical results of limb salvage for primary malignant bone tumor of the distal tibia using block excision of the tumor and reconstruction with allograft arthrodesis with different methods of fixation (plates or intramedullary nail system)

Detailed Summary:

It is well known that before the 1980`s the usual treatment for the sarcomas of the distal tibia was amputation (1). Currently, however, after the improvement of the chemotherapy treatments, potential reconstructions of the area in well studied patients are possible, and for that we have a wide range: auto graft, allograft and prosthetic reconstructions (2, 3)

Is important to know that osteosarcoma still meant the principal diagnosis, followed by the Ewing sarcoma and synovial sarcoma, but their malignant potency is lower than when they are present in the rest of the body (4, 5, and 6)

The purpose of this study is to recollect the patients' data followed from different institutions and countries that have the criteria for their inclusion in the study (primary malignant bone tumor of the distal tibia that underwent block excision of the tumor and reconstruction with allograft arthrodesis from the patient management for any of the multidisciplinary sarcoma team including in this study).


Sponsor: Patricia Bonilla

Current Primary Outcome: principal diagnosis of the patients that wen trough ankle after resection of a primary malignant tumor of the distal tibia [ Time Frame: 1 month ]

osteosarcoma: 5 patientas (2 females of 18 and 15 years old and 3 males of 19, 24 and 16 years old) telangiectasic osteosarcoma (1 female of 21 years old) Ewing sarcoma (1 male of 33 years old)


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • mobility [ Time Frame: 5 month to 10 years follow up ]
    surgical site infection, non union, malunion, osteosynthesis material failure
  • mortality [ Time Frame: 5 months to 10 years follow up ]
    secundary of the primary tumor diagnosis or metastatic disease of it
  • MSTS SCORE [ Time Frame: 5 month to 10 years follow up ]
    total points score of the msts score at the final follow up


Original Secondary Outcome: Same as current

Information By: Hospital del Niño "Dr. José Renán Esquivel"

Dates:
Date Received: October 13, 2015
Date Started: May 20, 2017
Date Completion: March 31, 2018
Last Updated: April 25, 2017
Last Verified: April 2017