Clinical Trial: Effect of HABIT-ILE on Visuo-spatial Attention of Children With Unilateral CP

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Effect of Rehabilitation in Deficiencies, Activities Limitations and Restrictions of the Participation of the Children Presenting Neurological Lesions. Impact of Contextual Factors on the Functioning

Brief Summary: This study aims to investigate the changes induced by HABIT-ILE in impairments, activity and participation of children with unilateral CP, as well as neuroplastic changes induces by the treatment. Visuospatial deficits will be investigated and the effect of prismatic adaptation will be measured.

Detailed Summary: This study aims to investigate the changes induced by HABIT-ILE at the 3 levels of the international classification of functioning and health (ICF) in children with unilateral CP, as well as neuroplastic changes induces by the treatment. Visuospatial deficits will be investigated and the effect of prismatic adaptation will be measured.
Sponsor: Université Catholique de Louvain

Current Primary Outcome:

  • changes in star cancellation [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    number of little stars omitted in a frame including many stars of different size
  • change in Ogden Figure [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    number of elements omitted when reproducing a drawing
  • changes in line bissection [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    deviation from midline during line section
  • visuo-spatial pointing [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    pointing in a blind box in the direction of a visual cue, measuring the deviation from midline
  • proprioceptive pointing [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    pointing without any visual feedback in the direction of bedy midline and measuring deviation


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Jebsen-Taylor test of hand function [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    Manual dexterity measured with objects of everydaylife, measure=time to manipulate objects
  • functional magnetic resonance imaging (fMRI) [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    cortical activation (changes in voxels activation)
  • Box and blocks [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    number of blocks manipulated in one minute
  • Assisting Hand Assessment [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    help provided by the paretic hand to the non-paretic one in bimanual coordination
  • ABILHAND-Kids [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    parents-reported questionnaire measuring manual ability
  • ACTIVLIM-CP [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    parents-reported questionnaire measuring global activity performance
  • Canadian Occupationnal Performance Measure [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    setting therapeutic goals with parents and measuring both performance and satisfaction (%)
  • diffusion tensor imaging (DDTI) [ Time Frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention ]
    measuring changes in white matter tracts (fractional anisotropy, number of voxels)


Original Secondary Outcome: Same as current

Information By: Université Catholique de Louvain

Dates:
Date Received: December 21, 2015
Date Started: April 2013
Date Completion:
Last Updated: October 24, 2016
Last Verified: October 2016