Clinical Trial: Prospective Study on Plasma Pro-endothelin-1 in Predicting Bronchopulmonary Dysplasia

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Prospective Study on Plasma Pro-endothelin-1 in Predicting Bronchopulmonary Dysplasia

Brief Summary: Serial quantitative measurements of plasma pro-endothelin-1 concentrations in very preterm infants. Comparing pro-endothelin-1 with established clinical indices of bronchopulmonary dysplasia (BPD). Hypothesis: Pulmonary-vascular remodeling in infants developing BPD is directly related to circulating pro-endothelin-1, which therefore serves as surrogate marker of BPD.

Detailed Summary:
Sponsor: University of Zurich

Current Primary Outcome: duration of supplemental oxygen requirement [ Time Frame: 36 weeks postmenstrual age ]

Bronchopulmonary dysplasia


Original Primary Outcome:

Current Secondary Outcome: duration of respiratory pressure support [ Time Frame: during hospitalisation ]

respiratory pressure support either mechanical and/or nCPAP (days)


Original Secondary Outcome:

Information By: University of Zurich

Dates:
Date Received: July 17, 2012
Date Started: May 2012
Date Completion:
Last Updated: May 9, 2016
Last Verified: May 2016