Clinical Trial: Efficacy of Dark Chocolate in Achalasia Patients

Study Status: Active, not recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Efficacy of Dark Chocolate in Achalasia Patients: Placebo-Controlled Study

Brief Summary:

Flavanols, present in dark chocolate, were shown to induce Nitric Oxide synthesis. Since Nitric Oxide facilitates smooth muscle relaxation, it might ease the relaxation of the LES (lower esophageal sphincter)as well.

The objective of the present study is to evaluate tha efficacy of dark chocolate in improving LES relaxation in achalasia patients.

Detailed Summary:
Sponsor: Tel-Aviv Sourasky Medical Center

Current Primary Outcome: Lower Esophageal Sphincter relaxation before and after dark chocolate consumption. [ Time Frame: day 1 ]

Original Primary Outcome: Same as current

Current Secondary Outcome: achalasia symptoms before and during dark-chocolate consumption [ Time Frame: 2 weeks ]

Original Secondary Outcome: Same as current

Information By: Tel-Aviv Sourasky Medical Center

Dates:
Date Received: November 12, 2008
Date Started: November 2008
Date Completion: November 2010
Last Updated: November 12, 2008
Last Verified: November 2008