Clinical Trial: Impulsivity and Stimulant Administration
Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional
Official Title: Impulsivity and Stimulant Administration
Brief Summary: Examine the interaction between stimulants, such as cocaine and methylphenidate, and impulsivity.
Detailed Summary:
Sponsor: Yale University
Current Primary Outcome: Mean cocaine inter-infusion interval [ Time Frame: 3 hours ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Stop Signal Reaction Time (Impulsivity) [ Time Frame: 5 years ]The Dependent measures pertinent to the effects of an acute/chronic exposure to stimulants (methylphenidate/cocaine) on measures of impulsivity will be analyzed using a mixed design ANOVA. This design will have a within subjects variable to study the effects of an acute exposure to stimulants (methylphenidate vs. placebo) and a between subjects variable to study the effects of a chronic exposure to stimulants (cocaine dependent subjects vs. healthy controls).
- Inter-Temporal Choice (Impulsivity) [ Time Frame: 5 years ]The Dependent measures pertinent to the effects of an acute/chronic exposure to stimulants (methylphenidate/cocaine) on measures of impulsivity will be analyzed using a mixed design ANOVA. This design will have a within subjects variable to study the effects of an acute exposure to stimulants (methylphenidate vs. placebo) and a between subjects variable to study the effects of a chronic exposure to stimulants (cocaine dependent subjects vs. healthy controls).
Original Secondary Outcome: Same as current
Information By: Yale University
Dates:
Date Received: October 17, 2013
Date Started: November 2012
Date Completion:
Last Updated: June 22, 2016
Last Verified: June 2016