Clinical Trial: Serotonin, Impulsivity, and Cocaine Dependence Treatment

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Serotonin, Impulsivity, and Cocaine Dependence Treatment

Brief Summary: The purpose of this study is to compare the effects of citalopram versus placebo given in the context of contingency management for cocaine dependence.

Detailed Summary: Cocaine dependence continues to be a significant public health problem, for which there is no FDA approved pharmacotherapy. This study is a 12-week, double blind, placebo controlled trial of citalopram for cocaine dependence. The primary outcome measure is benzoylecgonine positive urines. Secondary measures of side effects and craving are also examined.
Sponsor: National Institute on Drug Abuse (NIDA)

Current Primary Outcome: The presence of cocaine metabolites in urine weekly.

Original Primary Outcome: Same as current

Current Secondary Outcome: Retention rate and cocaine cravings weekly.

Original Secondary Outcome: Same as current

Information By: National Institute on Drug Abuse (NIDA)

Dates:
Date Received: February 27, 2006
Date Started: April 2001
Date Completion: November 2004
Last Updated: January 11, 2017
Last Verified: February 2006