Clinical Trial: Measurement of Neonatal Microvascular Hemodynamics Using Non-invasive Optical Technologies

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Measurement of Neonatal Microvascular Hemodynamics Using Non-invasive Optical Technologies

Brief Summary:

Alterations to microvascular blood flow in premature infants, are known to contribute to several major disease entities.

The optically-measured tissue blood flow, to determine tissue perfusion that can be use to detect blood loss.

Detailed Summary:

The researchers want to use optical technologies to non-invasively detect blood flow that can tell the onset of blood loss. The research can measure blood flow in stable premature infants in the Neonatal Intensive Care Unit over the duration of several weeks.

The technologies are Laser Speckle Imaging and Diffuse Optical Spectroscopy.

Laser Speckle Imaging non-contact imaging technology, is sensitive to blood flow in superficial tissues. Diffuse Optical Spectroscopy, a probe-based contact technology like pulse oximetry, measures hemoglobin concentrations and states deeper below the skin surface.

Sponsor: University of California, Irvine

Current Primary Outcome: Normal Blood flow in premature infant [ Time Frame: up to 4 weeks ]

Original Primary Outcome: changes in tissue blood flow in premature infants. [ Time Frame: appoximately within 5 minutes ]

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of California, Irvine

Dates:
Date Received: November 5, 2013
Date Started: July 2013
Date Completion: July 2018
Last Updated: February 8, 2017
Last Verified: February 2017