Clinical Trial: Effects of Laser Acupuncture Therapy on Paralytic Ileus

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Effects of Laser Acupuncture Therapy on Paralytic Ileus

Brief Summary: Ileus occurs from hypomotility of the gastrointestinal tract. Causes of Paralytic ileus include post-operation, stroke, and bed-ridden for a long time. Medicine treatment is less and less effective over time. Some study revealed that Moxibustion and Acupuncture are effective in Paralytic ileus. Investigators try to find other treatment except of medicine. Laser Acupuncture is a safe and non-invasive choice. This study is to evaluate effect of Laser Acupuncture on Paralytic ileus.

Detailed Summary:

This study's sample consisted of 94 adult participants who had Paralytic ileus. Patients experiencing skin disease or wounds, pregnancy, less than 20 years old, and who take Immunosuppressants drugs or Morphine, Mechanical obstruction were excluded. These 94 patients were randomly divided into two groups: a Laser Acupuncture group and a control group. At the beginning of study, check X-ray(KUB), collect serum Gastrin, Motilin, and Pancreatic polypeptide, and record bowel sound per minute, frequent of enema, average amount of stool per day. 47 patients received Laser Acupuncture therapy three times a week in acupoints RN6, RN4, and RN12. The whole duration of treatment is 8 weeks. The control group patients receive pseudo laser acupuncture. In the end of 4th and 8th week, check X-ray(KUB), collect serum Gastrin, Motilin, and Pancreatic polypeptide, and record bowel sound per minute, observe the daily record and then calculate frequent of enema and average amount of stool per day. After the end of treatment, the investigators keep follow up for 4 weeks. The outcome parameters include:

  1. KUB,
  2. the average amount of stool every day,
  3. frequency of bowel sound,
  4. frequency of enema, (Indication of enema: the amount of stool less than 200g within 3 days),
  5. the change of serum Gastrin, Motilin, and Pancreatic polypeptide.

Sponsor: China Medical University Hospital

Current Primary Outcome: the changing of diameter of colon (KUB) [ Time Frame: the 4th, 8th, 12th week ]

Definition of Ileus: Diameter of colon: >6cm. Check KUB on the 4th, 8th, 12th week. Calculate the biggest diameter of colon. Is diameter of colon decreasing in Laser Acupuncture group?


Original Primary Outcome: Same as current

Current Secondary Outcome: the average amount of stool per day(g/Day) [ Time Frame: the 4th, 8th, 12th week ]

Is the average amount of stool per day elevating in laser group?


Original Secondary Outcome: Same as current

Information By: China Medical University Hospital

Dates:
Date Received: January 23, 2017
Date Started: February 13, 2017
Date Completion: August 31, 2017
Last Updated: February 5, 2017
Last Verified: February 2017