Clinical Trial: The Study of Using Esophageal Pressure to Guide the PEEP Setting in Abdominal Hypertension Patients Who Undergoing Mechanical Ventilation
Study Status: Enrolling by invitation
Recruit Status: Unknown status
Study Type: Interventional
Official Title: the Study of Using Esophageal Pressure to Guide the PEEP Setting in Abdominal Hypertension Patients Who Undergoing Mechanical Ventilation
Brief Summary: Intra-abdominal hypertension can increase the pleural pressure, and then end-expiratory transpulmonary pressures will be turn to negative, Pulmonary atelectasis/acute lung injury/acute respiratory distress syndrome will appear. In the group of people who suffering intra-abdominal hypertension, the investigators use the pressure of esophagus to speculate the Intrathoracic pressure, and to setting PEEP in order to decrease the happening of ALI/ARDS, which may decrease morbidity in this population.
Detailed Summary:
Sponsor: Nanjing Medical University
Current Primary Outcome: ventilator-free days [ Time Frame: 28d ]
Original Primary Outcome: Same as current
Current Secondary Outcome: mortality [ Time Frame: 28d ]
Original Secondary Outcome: Same as current
Information By: Nanjing Medical University
Dates:
Date Received: April 2, 2013
Date Started: October 2011
Date Completion: June 2013
Last Updated: April 4, 2013
Last Verified: October 2011