Clinical Trial: The Use of Near Infrared Spectroscopy (NIRS) to Estimate Intracranial Pressure (ICP)

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: The Use of Near Infrared Spectroscopy (NIRS) to Estimate Intracranial Pressure (ICP)

Brief Summary: The aim of this study is to determine whether we can predict the intracranial pressure using near infra-red spectroscopy

Detailed Summary:

The management of intracranial hypertension requires the presence of an intracranial pressure monitor. We are investigating whether the waveforms obtained from a near infrared spectroscopy device can predict what the intracranial pressure is non-invasively.

  • Patients with intracranial hypertension who are intubated and ventilated in the ICU will be recruited
  • we will record there intracranial pressure and systemic arterial pressure
  • recordings from the near infrared device will be recorded and analysed off-line
  • we will correlate the waveform tracings from near infrared spectroscopy and the arterial tracing

Sponsor: University of Virginia

Current Primary Outcome: Intracranial elastance [ Time Frame: Participants will be followed while an arterial line and intracranial pressure monitor is present duing the ICU admission. This is expected to be an average of 5 days. ]

Intracranial elastance (δP/δV)will be measured by dividing the pulse pressure of an invasive arterial blood pressure by the amplitude of high frequency oscillations in the near infrared (NIR) absorbance waveforms.


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Virginia

Dates:
Date Received: April 25, 2013
Date Started: June 2014
Date Completion: June 2017
Last Updated: October 24, 2016
Last Verified: October 2016