Clinical Trial: Hemodilution and Outcome in Cardiac Surgery

Study Status: Terminated
Recruit Status: Terminated
Study Type: Interventional

Official Title: Effect of Moderate Hemodilution During Cardiopulmonary Bypass on Postoperative Outcome Following Cardiac Surgery

Brief Summary:

An hematocrit of 21-25% is supposed to perform the best organ protection during cardiopulmonary bypass for cardiac surgery.

The investigators want to establish the best timing for a transfusion (in patients with a predicted low hematocrit during cardiopulmonary bypass) and the efficacy of preprocedural hemodilution (in patients with a predicted high hematocrit during cardiopulmonary bypass) in patients undergoing cardiac surgery.


Detailed Summary:
Sponsor: Università Vita-Salute San Raffaele

Current Primary Outcome: renal function

Original Primary Outcome: Same as current

Current Secondary Outcome:

  • other organ damage
  • prolonged mechanical ventilation, Intensive Care Unit (ICU) and hospital stay
  • sepsis
  • exitus


Original Secondary Outcome:

  • other organ damage
  • prolonged mechanical ventilation, ICU and Hospital stay
  • sepsis
  • exitus


Information By: Università Vita-Salute San Raffaele

Dates:
Date Received: August 11, 2006
Date Started: November 2006
Date Completion:
Last Updated: August 13, 2009
Last Verified: August 2009