Clinical Trial: Systematic Follow up of Drug Treatment by Pharmacists in Secondary Prevention After Transient Ischemic Attack

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Systematic Follow up of Drug Treatment by Pharmacists in Secondary Prevention After Transient Ischemic Attack: Adherence and Cardiovascular Events in the First Three Month

Brief Summary: Use of drugs is an important factor in secondary prophylaxis after transient ischemic attack (TIA), but studies show that adherence to the prescribed drugs is often poor. This randomised controlled trial aims to investigate whether a systematic follow up of drug treatment using medication reconciliation, medication reviews and patient counselling by clinical pharmacists, improves adherence and/or decreases cardiovascular events the first three months and the first year after TIA. Patient satisfaction will also be compared between the two groups.

Detailed Summary:
Sponsor: Norwegian University of Science and Technology

Current Primary Outcome: adherence to drug treatment in secondary prevention after TIA [ Time Frame: 3 months ]

self reporting of adherence


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • adherence to drug treatment in secondary prevention after TIA [ Time Frame: 1 year ]
    self reporting of adherence
  • Persistence [ Time Frame: 3 months ]
    Persistence measured by control of filled prescriptions
  • Incidence of stroke and cardiovascular events and deaths [ Time Frame: 3 months ]
    Measured by using data from national health registries
  • degree of disability or dependence in the daily activities [ Time Frame: 3 months ]
    measured by modified Rankin Scale and indirectly by level of care
  • patient satisfaction [ Time Frame: 3 months ]
    Measured by using data from the Norwegian Stroke Registry
  • Persistence [ Time Frame: 1 year ]
    Persistence measured by control of filled prescriptions
  • Incidence of stroke and cardiovascular events and deaths [ Time Frame: 1 year ]
    Measured by using data from national health registries
  • degree of disability or dependence in the daily activities [ Time Frame: 1 year ]
    measured by modified Rankin Scale and indirectly by level of care
  • patient satisfaction [ Time Frame: 1 year ]
    Measured by using data from the Norwegian Stroke Registry


Original Secondary Outcome: Same as current

Information By: Norwegian University of Science and Technology

Dates:
Date Received: March 13, 2014
Date Started: November 2012
Date Completion:
Last Updated: March 29, 2017
Last Verified: March 2017