Clinical Trial: 2.5% and 10% Phenylephrine for Mydriasis in Diabetic Patients With Darkly Pigmented Irides

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: 2.5% and 10% Phenylephrine for Mydriasis in Diabetic Patients With Darkly Pigmented Irides

Brief Summary: To compare the clinical efficacy and systemic side effects between 2.5% and 10% phenylephrine for mydriasis in diabetic patient with darkly pigmented irides.

Detailed Summary: One hundred patients with diabetes from Srinagarind Hospital Eye Clinic were enrolled and randomized into two groups by block randomization. In group I (50 patients), 1% tropicamide combined with 2.5% phenylephrine were administered to dilate pupil whereas 1% tropicamide combined with 10% phenylephrine were used in Group II (50 patients). Pupil diameter, blood pressure and heart rate were measured before and after eye drop instillations.
Sponsor: Khon Kaen University

Current Primary Outcome: Pupil diameters were measured. [ Time Frame: before and after phenylephrine eye drop instillations ]

Original Primary Outcome: Same as current

Current Secondary Outcome: blood pressure and heart rate were measured [ Time Frame: before and after phenylephrine eye drop instillations ]

Original Secondary Outcome: Same as current

Information By: Khon Kaen University

Dates:
Date Received: July 13, 2007
Date Started: May 2007
Date Completion:
Last Updated: March 7, 2012
Last Verified: March 2012