Clinical Trial: Integrative Analysis of CRC Liver Metastasis
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational
Official Title: Integrative Analysis of CRC Liver Metastasis
Brief Summary: The investigators will perform integrative analysis of CRC liver metastasis
Detailed Summary: The investigators will analyzed proteomes of paired normal colorectal tissues and colorectal cancer (CRC) with or without liver metastasis, sequenced transcriptomes, performed whole exome sequencing, and single nucleotide polymorphism (SNP) array profiling for triplets, each comprising normal colorectal tissue, primary colorectal carcinoma, and its synchronous matched liver metastasis, as well as analyzed genomics of CRC characterized previously by The Cancer Genome Atlas (TCGA) to conduct integrated proteogenomic analyses.
Sponsor: Da Fu
Current Primary Outcome: 5 years overall survival [ Time Frame: 5 years ]
Original Primary Outcome: Same as current
Current Secondary Outcome: 5 years disease-free survival [ Time Frame: 5 years ]
Original Secondary Outcome: Same as current
Information By: Shanghai 10th People's Hospital
Dates:
Date Received: September 26, 2016
Date Started: January 2016
Date Completion: December 2026
Last Updated: September 27, 2016
Last Verified: September 2016