Clinical Trial: Application Value of CTCs Detection for Advanced Gastric Cancer Patients

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational [Patient Registry]

Official Title: A Single Center Observational Study to Evaluate the Application Value of Circulating Tumor Cell Detection for Advanced Gastric Cancer Patients in Prediction of the Prognos

Brief Summary: Evaluating the application value of a new circulating tumor cell detection method for advanced gastric cancer patients in prediction of the prognosis and early evaluation of the result of postoperation adjuvant chemotherapy.

Detailed Summary:
Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Current Primary Outcome: Number of circulating tumor cell (CTC) [ Time Frame: Up to 2 years from start of study ]

Number of the circulating tumor cell in peripheral blood from advanced gastric cancer patients undergoing D2 radical resection followed by first-line chemotherapy


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Profile and Portion of circulating tumor cell (CTC) [ Time Frame: Up to 2 years from start of study ]
    Profile and Portion of the circulating tumor cell in peripheral blood from advanced gastric cancer patients undergoing D2 radical resection followed by first-line chemotherapy. There are three type of CTCs: epithelial type CTC，mesenchymal type CTC and mixed type CTC. The portion of different type of CTC were calculated, for example: the portion of epithelia type CTC number to total CTCs,etc.
  • Progression-free survival [ Time Frame: Up to 3 years from start of the study ]
    Survival duration since radical resection to clinical finding of relapse disease.
  • Overall survival [ Time Frame: Up to 5 years from start of the study ]
    Survival duration since radical resection to patient die.


Original Secondary Outcome: Same as current

Information By: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Dates:
Date Received: November 30, 2016
Date Started: January 2016
Date Completion: December 2020
Last Updated: May 15, 2017
Last Verified: November 2016