Clinical Trial: The Relationship Between Sleep and Glucose Tolerance in Prediabetes: the Role of GLP-1 in Short Sleepers

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: The Relationship Between Sleep and Glucose Tolerance in Prediabetes: the Role of GLP-1 in Short Sleepers

Brief Summary:

Hypothesis

  1. Prediabetes patients who have insufficient sleep will have worse glucose tolerance than those with normal sleep duration.
  2. Prediabetes patients with short sleep will have a delayed or reduced GLP-1 response to a standardized meal

Detailed Summary:
Sponsor: Ramathibodi Hospital

Current Primary Outcome: GLP-1 levels in response to oral glucose tolerance test [ Time Frame: 2 weeks ]

Prediabetes patients with and without short sleep will undergo an oral glucose tolerance test with measurement of GLP-1 levels


Original Primary Outcome: GLP-1 levels in response to mixed meal test [ Time Frame: 2 weeks ]

Prediabetes patients with and without short sleep will undergo a mixed meal test with measurement of GLP-1 levels


Current Secondary Outcome:

Original Secondary Outcome:

Information By: Ramathibodi Hospital

Dates:
Date Received: August 28, 2014
Date Started: October 2014
Date Completion:
Last Updated: April 11, 2017
Last Verified: April 2017