Clinical Trial: Cognitive Determinants of Psychoeducation and Information in Psychoses
Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Psychoeducation in Patients With Schizophrenia: Neuropsychological Performance and Cognitive Training as Determinants of Outcome
Brief Summary: The aim of the study is to examine whether the efficacy of psychoeducation in patients with schizophrenia or schizoaffective disorders is dependent on their cognitive performance level and if a preceding cognitive training can enhance the therapeutic effects of psychoeducation
Detailed Summary: Schizophrenic inpatients are examined shortly after admission with a broad battery of clinical and neurological rating scales and neuropsychological tests. They are then randomized to either standard treatment (including antipsychotic medications, art and occupational therapy, psychotherapy) or to standard treatment plus daily computerbased cognitive training (COGPACK; ten 1-hour sessions over two weeks). After repetition of the broad assessment battery all patients (and some of their family members) take part in a bifocal psychoeducation group program (eight 1-hour sessions over four weeks). Specific pre-post measures are illness knowledge, self and expert ratings of adherence to treatment, insight to the illness, treatment satisfaction. The study also includes a 9-month follow-up, with number of rehospitalizations, days in hospital and psychopathology as the primary outcome measures.
Sponsor: German Research Foundation
Current Primary Outcome: illness knowledge, adherence to treatment, insight to the illness, satisfaction with treatment. 9-month follow-up: number of rehospitalizations, days in hospital [ Time Frame: Baseline, after cognitive training, after psychoeducation, 9-month after end of psychoeducation ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Psychopathological status
- Psychosocial rehabilitation
Original Secondary Outcome: Same as current
Information By: German Research Foundation
Dates:
Date Received: March 25, 2008
Date Started: February 2006
Date Completion:
Last Updated: March 25, 2008
Last Verified: March 2008