Clinical Trial: Complete Mesocolon Excision vs Locoregional Lymphadenectomy in Sigmoid Colon Cancer (CMELL)
Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional
Official Title: Complete Mesocolon Excision vs Locoregional Lymphadenectomy in Sigmoid Colon Cancer (CMELL)
Brief Summary: A randomized, controlled clinical trial comparing lymphadenectomy with extended inferior mesenteric artery ligation (complete mesocolon excision: which includes lymphoma tissue from the origin of the inferior mesenteric vein) with conventional locoregional lymphadenectomy in patients undergoing laparoscopic sigmoidectomy for sigmoid cancer.
Detailed Summary:
Sponsor: Pere Planellas Giné
Current Primary Outcome: Total number of lymph nodes and lymph node ratio. [ Time Frame: 30 days ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Local recurrence [ Time Frame: 5 years ]To compare the tumor local recurrence rate between the two arms.
- Survival [ Time Frame: 5 years ]To compare the survival rate (deaths from cancer) between the two arms
Original Secondary Outcome: Same as current
Information By: Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Dates:
Date Received: March 2, 2017
Date Started: July 2017
Date Completion: March 2023
Last Updated: March 13, 2017
Last Verified: March 2017