Clinical Trial: Impact of EDUcation Strategy on Patients With COLorectal CANCER or Advanced Adenoma in the Detection of Colorectal Cancer of Their First-degree Relatives

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Impact of EDUcation Strategy on Patients With COLorectal CANCER or Advanced Adenoma in the Detection of Colorectal Cancer of Their First-degree Relatives - Randomized, Mul

Brief Summary:

The relative risk of colorectal cancer (CRC) is increased in first-degree relatives of patients with CRC or advanced adenoma. In the high-risk CCR population defined by a family history at the first stage of CRC or advanced adenoma before age 60, total colonoscopy is the recommended screening test. In France, the rate of screening colonoscopy in this population at high risk of CRC is insufficient, which limits the effectiveness of this targeted screening.

The main reason for this low participation rate is that most patients undergoing RCC or advanced adenoma are unaware of the family implications of their diagnosis and therefore reluctant to disseminate this information to their patients Related matters. The need for a better perception of the personal risk of CRC in first-degree relatives of patients with CRC or advanced adenoma, with the expected coronary adherence to increasing screening, requires a good understanding of risk through Clear, adapted and comprehensible information that can be relayed personally by the case-index.

The objective of this project is to develop a personalized prevention and screening program for the JRC in order to meet the needs of the relatives of the sick. The means of intervention that will be implemented respond to the need to better take into account the level of CRC risk in a family-based CRC screening and prevention approach adapted to a high-risk CRC group characterized by Family history at the first stage of CRC or advanced adenoma and, consequently, to improve the information of the subjects concerned by screening and prevention of CRC.

The aim of the case-index education is to induce its intervention with its relatives to promote CCR screening. The use of the index case, as a means of providing information to relatives, implies an e

Detailed Summary: The relative risk of colorectal cancer (CRC) is increased in first-degree relatives of patients with CRC or advanced adenoma. In the high-risk CCR population defined by a family history at the first stage of CRC or advanced adenoma before age 60, total colonoscopy is the recommended screening test. In France, the rate of screening colonoscopy in this population at high risk of CRC is insufficient, which limits the effectiveness of this targeted screening.
Sponsor: University Hospital, Tours

Current Primary Outcome: Participation rate in screening colonoscopy for first-degree relatives of patients with RCC or advanced adenoma. [ Time Frame: 12 MONTHS ]

Participation rate in screening colonoscopy for first-degree relatives of patients with RCC or advanced adenoma.


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Psychological determinants (quality of relationship with relatives, motivation to inform relatives) that can condition the enrollment in the education program. [ Time Frame: 12 MONTHS ]
    Psychological determinants (quality of relationship with relatives, motivation to inform relatives) that can condition the enrollment in the education program.
  • Social and demographic factors in index cases associated with screening colonoscopy in related subjects: age, sex, educational level, socio-professional category. [ Time Frame: 12 MONTHS ]
    Social and demographic factors in index cases associated with screening colonoscopy in related subjects: age, sex, educational level, socio-professional category.
  • Social and demographic factors associated with screening colonoscopy in related subjects: age, sex, educational level, socio-professional category. [ Time Frame: 12 MONTHS ]
    Social and demographic factors associated with screening colonoscopy in related subjects: age, sex, educational level, socio-professional category.
  • How to access screening colonoscopy: pathway (public or private), direct access to the gastroenterologist or through the attending physician. [ Time Frame: 12 MONTHS ]
    How to access screening colonoscopy: pathway (public or private), direct access to the gastroenterologist or through the attending physician.
  • Time to access the colonoscopy (time between the procedure and the completion of the screening colonoscopy). [ Time Frame: 2 MONTHS ]
    Time to access the colonoscopy (time between the procedure and the completion of the screening colonoscopy).
  • Rate of colorectal cancer. [ Time Frame: 12 MONTHS ]
    Rate of colorectal cancer.
  • Rate of advanced adenomas. [ Time Frame: 12 MONTHS ]
    Rate of advanced adenomas.
  • Detection rate of scallop lesions. [ Time Frame: 12 MONTHS ]
    Detection rate of scallop lesions.
  • Rate of complications in screening colonoscopies. [ Time Frame: 12 MONTHS ]
    Rate of complications in screening colonoscopies.
  • Quality criteria for screening colonoscopy using the following parameters: visualization rate of the bottom of the colon, the withdrawal time of the colonoscope (Withdrawal time), quality of the colic preparation using the Boston scale. [ Time Frame: 12 MONTHS ]
    Quality criteria for screening colonoscopy using the following parameters: visualization rate of the bottom of the colon, the withdrawal time of the colonoscope (Withdrawal time), quality of the colic preparation using the Boston scale.


Original Secondary Outcome: Same as current

Information By: University Hospital, Tours

Dates:
Date Received: February 28, 2017
Date Started: April 10, 2017
Date Completion: June 3, 2019
Last Updated: May 5, 2017
Last Verified: May 2017