Clinical Trial: Aspirin/Folate Prevention of Large Bowel Polyps
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Aspirin/Folate Prevention of Large Bowel Polyps
Brief Summary: This is a randomized controlled trial of aspirin and/or folate supplementation for the prevention of the recurrence of neoplastic polyps (adenomas) of the large bowel.
Detailed Summary: This is a randomized controlled trial of aspirin and/or folate supplementation for the prevention of the recurrence of neoplastic polyps (adenomas) of the large bowel among subjects with a recent history of these tumors. The study is a randomized, double-blind, placebo-controlled trial with a 2 x 3 factorial design.
Sponsor: Dartmouth-Hitchcock Medical Center
Current Primary Outcome:
- colorectal adenomas during years 1-3 and years 4-8
- advanced colorectal adenomas during years 1-3 and years 4-8
- colorectal cancer
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Dartmouth-Hitchcock Medical Center
Dates:
Date Received: January 3, 2006
Date Started: February 1992
Date Completion: January 2007
Last Updated: January 3, 2006
Last Verified: November 2005
