Clinical Trial: Functional Outcomes of Stay Strong Stay Healthy Program

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Functional Outcomes of Stay Strong, Stay Healthy Program

Brief Summary: Strength training can increase muscle mass and strength while improving bone density and reducing risk for osteoporosis and related fractures. Strength training can also lead to reduced risk for diabetes, heart disease, arthritis, depression, and obesity; and improves self-confidence, sleep and vitality. Research demonstrates that strength training is extremely effective in helping aging adults with chronic conditions prevent further onset of disease and, in many instances, actually reverse the disease process. In Stay Strong, Stay Healthy Program elderly subjects perform resistance exercise training (RET) twice every week. Past literature suggests that resistance training improved muscle activity, muscle strength, muscle mass, and bone mineral density and total body composition, and adiponectin, insulin sensitivity, fasting blood-glucose (BG), HbA1c1 (long-term marker of BG), blood pressure (BP), blood triglycerides (TGs) and low density lipoproteins (LDL) in healthy and diabetic subjects. The purpose of this study is to measure the changes in the above discussed variables after 8-weeks of resistance exercises.

Detailed Summary: Participants will perform resistance exercise for 8 weeks and measurements (anthropometric, electromyography, pulse wave velocity, strength test, dual x-ray absorptiometry, blood enzymes/hormones, and sleep, diet, memory surveys) will be performed pre- and post-exercise program.
Sponsor: University of Missouri-Columbia

Current Primary Outcome: Muscle electrical activity [ Time Frame: Change in muscle electrical activity in 8 weeks in response to resistance exercise program ]

Measurement of muscle electrical activity is made using electromyography technique at baseline and after 8 weeks of resistance exercise.


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Exert muscle power/strength [ Time Frame: Change in muscle power/strength in 8 weeks in response to resistance exercise program ]
    Measurement of muscle power/strength is made using hand dynamometer at baseline and after 8 weeks of resistance exercise.
  • Muscle mass loss [ Time Frame: Change in muscle mass in 8 weeks in response to resistance exercise program ]
    Changes in the muscle mass is made using dual x-ray absorptiometry technique at baseline and after 8 weeks of resistance exercise.
  • Ability to think or remember [ Time Frame: Changes in thinking and cognitive abilities in 8 weeks in response to resistance exercise program ]
    Changes in ability to think or remember is measured by using standard survey (Self Administered Gerocognitive Exam Form -1) at baseline and after 8 weeks of resistance exercise.


Original Secondary Outcome: Same as current

Information By: University of Missouri-Columbia

Dates:
Date Received: February 2, 2016
Date Started: February 2016
Date Completion: December 2017
Last Updated: February 3, 2017
Last Verified: February 2017