Clinical Trial: A Study To Evaluate The Difference In iPad-Based Cognitive Video Game (Akili Interactive's Project: EVO) Performance In Amyloid-Positive Versus Amyloid-Negative Healthy Elderly Volunteers

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: A Randomized, Double Blind, Placebo Controlled Trial To Study Difference In Cognitive Learning Associated With Repeated Self-administration Of Remote Computer Tablet-based Application Assessing Dual-t

Brief Summary: The purpose of the study is to evaluate the difference in learning and performance measures associated with repeated use of an iPad video game (Akili Interactive's Project: EVO) in healthy elderly volunteers based on amyloid status.

Detailed Summary:
Sponsor: Pfizer

Current Primary Outcome: divided attention performance [ Time Frame: Day 0 - Day 28 ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

• sustained attention, impulsivity and episodic memory [ Time Frame: Day 0 - Day 28 ]
  The difference in effect of cognitive training on sustained attention, impulsivity and episodic memory as measured by the pre/post training change in performance at day 28
• perforamce on EVO dual task assessment, TOVA and RAVLT [ Time Frame: Day 0 - Day 28 ]
  The performance on EVO dual task assessment, Test of Variables of Attention (TOVA and Rey Auditory Verbal Learning Test (RAVLT) as measured by the pre and post training scores at Day 0 and Day 28
• within subject change on EVO, TOVA and RAVLT [ Time Frame: Day 0 - Day 28 ]
  The within subject change on EVO dual task assessment, TOVA and RAVLT between day -28 and Day 0.

Original Secondary Outcome: Same as current

Information By: Pfizer

Dates:
Date Received: October 13, 2014
Date Started: September 2014
Date Completion:
Last Updated: July 25, 2016
Last Verified: July 2016