Clinical Trial: Comparing the Adenoma Detection Rate With Air Insufflation, Water Immersion and Water Exchange

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: A Randomized, Controlled Trial Comparing the Adenoma Detection Rate With Air Insufflation, Water Immersion and Water Exchange During Colonoscopy

Brief Summary: Interval (missed) cancers and lower than expected mortality reduction of proximal colon cancers in the United States and elsewhere after screening colonoscopy drew attention to quality indicators. Missed adenomas which are more likely to be in the proximal colon may be contributing factors. An independent predictor of the risk of interval cancers is adenoma detection rate. In pilot observations, the investigators showed that water exchange enhanced adenoma detection in the right colon (cecum to hepatic flexure). This prospective, randomized controlled trial will compare water exchange with water immersion and traditional air insufflation in patients undergoing colonoscopy. The investigators test the hypothesis that compared with air insufflation and water immersion, water exchange produces a significantly higher adenoma detection rate in the right colon.

Detailed Summary: All of the procedures will be recorded and stored as digital files.
Sponsor: Dalin Tzu Chi General Hospital

Current Primary Outcome: adenoma detection rate [ Time Frame: one week ]

Original Primary Outcome: adenoma detection rate in the right colon [ Time Frame: one week ]

Current Secondary Outcome: adenoma detection rate in proximal colon [ Time Frame: one week ]

Original Secondary Outcome:

Information By: Dalin Tzu Chi General Hospital

Dates:
Date Received: July 3, 2013
Date Started: May 2013
Date Completion:
Last Updated: June 27, 2016
Last Verified: June 2016