Clinical Trial: Long-term Beneficial Metabolic Effects of Adrenalectomy in Subclinical Cushing's Syndrome of Adrenal Incidentaloma

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Long-term Effects of Adrenalectomy on Metabolic Syndrome, Glucose Metabolism, Lipid Metabolism, and Bone Metabolism in Subclinical Cushing's Syndrome of Adrenal Incidentaloma

Brief Summary:

Objective:

To determine the metabolic effects of the adrenalectomy in subclinical Cushing's syndrome of adrenal incidentaloma.

Methods:

234 subclinical cushing syndrome and adrenal incidentaloma will be randomly assigned into two groups(e.g adrenalectomy group and conservative treatment group).


Detailed Summary:
Sponsor: Samsung Medical Center

Current Primary Outcome: Change of lipid profile between two groups [ Time Frame: 4 Year ]

lipid profile with LDL,apo B


Original Primary Outcome: Same as current

Current Secondary Outcome: Incidence of obesity between two groups [ Time Frame: 4Year ]

measurement of body weight, height


Original Secondary Outcome: Same as current

Information By: Samsung Medical Center

Dates:
Date Received: May 30, 2011
Date Started: May 2011
Date Completion: May 2018
Last Updated: November 16, 2015
Last Verified: November 2015