Clinical Trial: Correlation of Albuminuria With Arterial Stiffness

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Assessment of the Association Between Albuminuria and Arterial Stiffness in Diabetic Patients, Hypertensive Patients and Healthy Controls

Brief Summary: The investigators aim to investigate the relationship between albuminuria and arterial stiffness in diabetic patients, hypertensive patients and healthy subjects.

Detailed Summary:

CONTEXT: Albuminuria is an important cardiovascular risk factor. Arterial stiffness also gives important information about atherosclerosis. Oscillometric methods may be useful in assessing arterial stiffness in a mainly operator independent way.

OBJECTIVE: We aim to investigate the relationship between albuminuria and arterial stiffness measured with an oscillometric device in diabetic patients, hypertensive patients and healthy subjects.

METHODS: 152 diabetic patients, 152 hypertensive patients and 152 healthy subjects are planned to be enrolled in this study. The measurements will be done between 9:00 and 13:00. After the measurements, blood and urine samples will be obtained, centrifugated and kept in -80°C until assayed. Afterwards, echocardiographic left ventricle mass index will be calculated. The correlation between albuminuria and arterial stiffness will be assessed as the primary outcome measure.

Sponsor: Istanbul University

Current Primary Outcome: Correlation between albuminuria and arterial stiffness [ Time Frame: Albuminuria and arterial stiffness will be assessed simultaneously (i.e. in the same morning) ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Istanbul University

Dates:
Date Received: December 30, 2009
Date Started: October 2009
Date Completion:
Last Updated: August 29, 2016
Last Verified: August 2016