Clinical Trial: A Feasibility Study for Growth Bone Vertically With Titanium Mesh and Allograft in Lower Posterior Jaw

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Vertical Ridge Augmentation Using Titanium Mesh and Allograft in Posterior Mandible: A Feasibility Study

Brief Summary:

This study will involve placing donor bone into the back of lower jaw then covering with a newly designed titanium mesh. The mesh will then stay in the mouth for 4 months before it will be removed. Implants will be placed in the newly formed bone.

The goal of this study is to test how well using a newly designed titanium mesh and bone particles can grow bone in the back of the lower jaw. The investigators are also checking if the newly formed bone will stay around implants that will have been in use for 12 months.


Detailed Summary:

Inclusion Criteria

  • Patients are at least 18 years old
  • At least two adjacent back teeth in the lower jaw are missing
  • No medical contraindication to dental surgery
  • Inadequate vertical ridge height at edentulous region (less than 10mm)

Exclusion Criteria

  • Unstable systemic diseases or conditions that would compromise the healing potential
  • Patients with osseous metabolic disorders (e.g., osteoporosis, Paget's disease etc.)
  • Patients who are pregnant or expect to get pregnant
  • Patients with unstable dental disease (e.g. caries and periodontitis) in the surgical sextant

Sponsor: University of Michigan

Current Primary Outcome: Bone Height [ Time Frame: 5 months ]

Diameter of the bone measured from the alveolar crest to the inferior alveolar nerve after the grafting procedures from CBCT images.


Original Primary Outcome: Implant Bone Loss [ Time Frame: 1 year ]

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Michigan

Dates:
Date Received: September 29, 2014
Date Started: September 2011
Date Completion:
Last Updated: January 27, 2017
Last Verified: January 2017