Clinical Trial: Bronchoalveolar Immune Response Determination

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Observational

Official Title: Study to Determine the Immune Response From Broncho-alveolar Cells Against Pigeon Specific Antigens

Brief Summary: The purpose of this study is to establish if cells present in lung tissue during extrinsic allergic alveolitis (EAA) are able to elicit an immune response against specific antigens. The hypothesis is: cells in BAL lavage fluid from patients with EAA will be responsive to specific antigens and this response can be measured using ELISPOT.

Detailed Summary: Subjects suffering from extrinsic allergic alveolitis caused by pigeons will undergo a broncho alveolar lavage. Cells obtained from this BAL will be used for ELISPOT technique with pigeon specific antigens
Sponsor: Bossink, A.W.J.

Current Primary Outcome: ELISPOT response in cells obtained from broncho-alveolar lavage [ Time Frame: 2 days ]

All elispots will be performed the same day, the end point will be available the next day


Original Primary Outcome: Same as current

Current Secondary Outcome: Elispot response in cells from blood [ Time Frame: 2 days ]

ELispots will be performed the same day as blood collection, results will be available the next day


Original Secondary Outcome: Same as current

Information By: Bossink, A.W.J.

Dates:
Date Received: November 7, 2010
Date Started: September 2011
Date Completion: December 2012
Last Updated: June 14, 2011
Last Verified: June 2011