Clinical Trial: Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma.
Brief Summary: The aim of this study is to investigate the change in iron metabolism in relation to malaria and helminth infections using a stable isotope technique.
Detailed Summary: The aim of the study is to determine how iron metabolism in subjects with infectious diseases (malaria, hookworm or S. haematobium) differs while infected and after treatment, i.e. the same individuals will be restudied while free of infection.
Sponsor: Swiss Federal Institute of Technology
Current Primary Outcome:
- Isotope absorption into blood stream [ Time Frame: Day 15 ]
- Isotope absorption into blood stream [ Time Frame: Day 43 ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Isotope incorporation into erythrocytes [ Time Frame: Day 15 ]
- Biochemical parameters of iron status and infection [ Time Frame: Day 1 ]
- Biochemical parameters of iron status and infection [ Time Frame: Day 15 ]
- Biochemical parameters of iron status and infection [ Time Frame: Day 29 ]
- Biochemical parameters of iron status and infection [ Time Frame: Day 43 ]
- Isotope incorporation into erythrocytes [ Time Frame: Day 43 ]
Original Secondary Outcome: Same as current
Information By: Swiss Federal Institute of Technology
Dates:
Date Received: July 14, 2010
Date Started: April 2010
Date Completion:
Last Updated: October 11, 2013
Last Verified: October 2013