Clinical Trial: A Histomorphometric Analysis Following Sinus Augmentation Using Two Different Bone Graft Materials.

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: A Histomorphometric Analysis of New Bone Formation Following Sinus Augmentation Using Two Different Bone Graft Materials. A Pilot Study in Humans.

Brief Summary: The purpose of this investigator-initiated study is to compare new bone formation through histomorphometric analysis following maxillary sinus augmentation using two different bone graft materials. A total of twenty, sinus augmentation via a lateral approach will be performed for subjects requiring sinus augmentation for implant placement and randomly divided into 2 groups. These subjects will receive one of two different bone graft materials: 1) Anorganic bovine bone matrix- InterOss (Group A), 2) Anorganic bovine bone matrix- Bio-oss (Group B). At the time of implant placement (eight months after the sinus augmentation procedure), two bone biopsies will be collected from augmented site for the histomorphometric analysis. The percentage of vital bone will be measured and analyzed statistically, also the following will be measured: percentage of non-vital bone, percentage of non-bone material (xenograft), and the percentage of connective tissue.

Detailed Summary:
Sponsor: Loma Linda University

Current Primary Outcome: Percentage of new vital bone [ Time Frame: 8 months ]

Vital bone as seen in histology


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Loma Linda University

Dates:
Date Received: February 16, 2017
Date Started: April 1, 2017
Date Completion: April 1, 2018
Last Updated: March 22, 2017
Last Verified: March 2017