Clinical Trial: Low Flow Low Gradient Aortic Stenosis Relevance of the (re)Search for a Contractile Reserve

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Low Flow Low Gradient Aortic Stenosis Relevance of the (re)Search for a Contractile Reserve

Brief Summary: Investigators sought to demonstrate that the increase in the stroke volume during a dobutamine stress echocardiography might impact the prognosis of a patient addressed for a low flow low gradient suspected severe aortic valve stenosis.

Detailed Summary:
Sponsor: Rennes University Hospital

Current Primary Outcome:

  • Number of death of all cause [ Time Frame: Month 12 ]
  • Number of emergent hospitalization for any cardiovascular reason [ Time Frame: Month 12 ]


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Death (all causes) [ Time Frame: 12 months ]
  • Emergency Cardiovascular hospitalization [ Time Frame: 12 months ]
  • Change in left ventricular ejection fraction (LVEF), in global longitudinal strain in 2D and or 3D echocardiography [ Time Frame: Inclusion, 12 months ]
  • Symptoms evolution [ Time Frame: Inclusion, 12 months ]
    6-minute walking test
  • Symptoms evolution [ Time Frame: Inclusion, 12 months ]
    Duke Activity Score


Original Secondary Outcome: Same as current

Information By: Rennes University Hospital

Dates:
Date Received: March 21, 2016
Date Started: May 2016
Date Completion: January 2019
Last Updated: November 3, 2016
Last Verified: November 2016