Clinical Trial: Study of the Effect of Oral Zinc Supplementation on Superoxide Radical Scavengers
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Study of the Effect of Oral Zinc Supplementation on Superoxide Radical Scavengers in Spermatozoa of Patients With Asthenospermia
Brief Summary: Although several studies have considered the relationship between infertility and semen super oxide radical scavengers levels, no study on the effects of asthenospermia treatments such as oral zinc supplementation on superoxide radical scavengers activity which are important in fertility of the individual has been reported.
Detailed Summary: The present study was conducted to study the effect of zinc supplementation on the quantitative and qualitative characteristics of semen along with superoxide radical scavengers activity in the seminal plasma of asthenospermic patients.
Sponsor: Babylon University
Current Primary Outcome: Oxido-sensitive index level in spermatozoa and seminal plasma. [ Time Frame: up to three months. ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Volume of semen. [ Time Frame: up to three months. ]
- Xanthine oxidase activity in spermatozoa and seminal plasma. [ Time Frame: up to three months. ]
- Catalase like activity in spermatozoa and seminal plasma. [ Time Frame: up to three months. ]
- Superoxide dismutase activity in spermatozoa and seminal plasma. [ Time Frame: up to three months. ]
- Progressive sperm motility percentage. [ Time Frame: up to three months ]
- Total normal sperm count. [ Time Frame: up to three months. ]
Original Secondary Outcome: Same as current
Information By: Babylon University
Dates:
Date Received: August 6, 2014
Date Started: July 2011
Date Completion:
Last Updated: February 1, 2017
Last Verified: February 2017
