Clinical Trial: The Effect of Oral Zinc Supplementation on Thiol Oxido-reductive Index
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: The Effect of Oral Zinc Supplementation on Thiol Oxido-reductive Index and Thiol Related Enzymes in Spermatozoa of Iraqi Asthenospermic Patients
Brief Summary: Although several studies have considered the relationship between infertility and semen thiol compounds levels, no study on the effects of asthenospermia treatments such as oral zinc supplementation on thiol related enzymes activity which are important in fertility of the individual has been reported.
Detailed Summary: The present study was conducted to study the effect of zinc supplementation on the quantitative and qualitative characteristics of semen along with reduced thiol, oxidized thiol and thiol related enzymes in the seminal plasma of asthenospermic patients.
Sponsor: mahmoud hussein hadwan
Current Primary Outcome: Thiol oxido-reductive index levels in spermatozoa and seminal plasma. The investigators evaluated the effects of zinc sulfate (220 mg/d) supplementation on Thiol oxido-reductive index levels. [ Time Frame: up to three months. ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Glutathione peroxidase activity levels in spermatozoa and seminal plasma. The investigators evaluated the effects of zinc sulfate (220 mg/d) supplementation on Glutathione peroxidase activity levels. [ Time Frame: up to three months. ]
- Sulfhydryl oxidase activity levels in spermatozoa and seminal plasma. The investigators evaluated the effects of zinc sulfate (220 mg/d) supplementation on Sulfhydryl oxidase activity levels. [ Time Frame: up to three months. ]
Original Secondary Outcome: Same as current
Information By: Babylon University
Dates:
Date Received: December 2, 2016
Date Started: July 2011
Date Completion:
Last Updated: December 6, 2016
Last Verified: December 2016
