Clinical Trial: Intra Testicular Artery Injection of Bone Marrow Stem Cell in Management of Azoospermia

Study Status: Not yet recruiting
Recruit Status: Unknown status
Study Type: Interventional

Official Title: Intra Testicular Artery Injection of Bone Marrow Stem Cell in Management of Azoospermia

Brief Summary: Azoospermia due to low sperm production (non-obstructive azoospermia) affects approximately 1% of the male population and 10% of men who seek fertility evaluation. Testis biopsy reveals that these men have Sertoli cell-only pattern, maturation arrest, or hypospermatogenesis. Until recently, it was assumed that men with non-obstructive azoospermia were untreatable. Indeed, these patients were often referred to as being "sterile" or having "testicular failure." We start to use stem cell in treatment of such patients by injecting the stem cell at the testis and the testicular artery in one group and at the testis only in other group

Detailed Summary:
Sponsor: Man Clinic for Andrology, Male Infertility and Sexual Dysfunction

Current Primary Outcome: Semen Analysis [ Time Frame: Three to six months ]

After stem cell injection by three to six months we evaluate the outcome by semen analysis


Original Primary Outcome: Same as current

Current Secondary Outcome: Inhibin B Hormone [ Time Frame: Three to six months ]

If semen analysis still azoo we do Inhibin B Hormone


Original Secondary Outcome: Same as current

Information By: Man Clinic for Andrology, Male Infertility and Sexual Dysfunction

Dates:
Date Received: December 8, 2013
Date Started: January 2013
Date Completion: December 2016
Last Updated: April 7, 2015
Last Verified: April 2015