Clinical Trial: FSH Treatment for Non-obstructive Azoospermic Patients
Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Follicle-stimulating Hormone Treatment for Infertile Male Patients With Non-obstructive Azoospermia: a Multicenter Randomized Clinical Trial
Brief Summary: Aim of the study is to evaluate the effect of highly purified human follicle-stimulating hormone treatment on the chance of retrieving testicular sperm (sperm retrieval rate) from infertile male patients with non-obstructive azoospermia of unknown origin.
Detailed Summary: Preliminary reports showed that hormonal treatment may improve the chance of retrieving viable testicular sperm from men with NOA, but no RCT are available in the field. This randomized placebo-controlled clinical trial sought to evaluate whether the testicular sperm retrieval rate could result higher in NOA patients treated with follicle-stimulating hormone compared to placebo-treated NOA subjects.
Sponsor: Azienda Sanitaria Locale Bari
Current Primary Outcome: Sperm retrieval rate (SRR) [ Time Frame: three months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- IVF pregnancy rate [ Time Frame: three to six months ]
- IVF implantation rate [ Time Frame: three to six months ]
Original Secondary Outcome: Same as current
Information By: Azienda Sanitaria Locale Bari
Dates:
Date Received: October 21, 2014
Date Started: February 2015
Date Completion: November 2016
Last Updated: January 30, 2015
Last Verified: January 2015